# MediLedger Product Verification System

> The MediLedger Product Verification System is a blockchain-based solution for the US pharmaceutical supply chain, developed by Chronicled in 2019 and acquired by the National Association of Boards of Pharmacy in 2023. The system enables tracking and verification of medications throughout the entire supply chain and supports compliance with US Drug Supply Chain Security Act regulations. Since launch, the platform processes transactions between manufacturers, distributors and pharmacies and has been integrated into NABP's Pulse platform since 2023.

**Sector:** Tertiary sector · **Industry:** Health technology · **Organisation:** Chronicled, Inc. (seit 2023 unter NABP) · **Maturity level:** Production

Canonical URL: https://www.sapientblock.com/en/use-cases/chronicled-arzneimittel-echtheit-pruefen

## Documentation status

- **Project status:** Production
- **Evidence:** Evidence high
- **Editorial review:** Ufuk Avci, 15 April 2026

## Description

The US Drug Supply Chain Security Act (DSCSA, 2013) mandates electronic traceability of all prescription medicines. Chronicled developed MediLedger — a blockchain network for DSCSA compliance based on Hyperledger Fabric. From November 2023, full interoperable electronic traceability is mandatory. NABP took over the Chronicled tool in June 2023 as a patient protection instrument.

Counterfeit medicines are a global problem: WHO estimates that 10% of all medicines worldwide are counterfeit, with an estimated 200,000 deaths per year. In the US, Congress responded in 2013 with the DSCSA, which mandates phased implementation of prescription medicine traceability. MediLedger (Chronicled, San Francisco) is the leading blockchain platform for this: it uses Hyperledger Fabric in a permissioned network where manufacturers, wholesalers, pharmacies and regulators have access. Each package receives a serial number; every transaction (shipment, receipt, return) is recorded on the blockchain. In case of suspected counterfeiting, a pharmacy can immediately query the full transaction history of the package. Partner network: Pfizer, Gilead, AmerisourceBergen, McKesson, Cardinal Health, Walmart, CVS Health and 100+ others. The FDA endorsed MediLedger as part of its DSCSA Pilot Program. In June 2023, NABP acquired the Chronicled tool to continue it as a non-profit patient protection instrument.

## Benefits

- Companies can meet regulatory requirements more efficiently and reduce compliance costs through automation.
- Patients gain greater safety in medicine supply through better combatting of counterfeits.
- The system increases transparency in the pharmaceutical supply chain through seamless documentation of all medicine transactions.
- Automated verification processes significantly reduce the time required for compliance checks.
- The decentralised architecture enables all supply chain participants to have equal access to verification data.
- Employees are relieved from time-consuming manual verification tasks and can focus on more value-adding activities.

## Challenges

- Companies must invest significant resources in technical integration and staff training.
- Integrating various ERP systems of supply chain participants requires customised interfaces and technical expertise.
- Challenges such as duplicate serial numbers and missing provenance data can impair system effectiveness.
- Employees must learn new workflows and become familiar with blockchain-based verification processes.

## Technology foundation

The MediLedger system uses a decentralized blockchain infrastructure specifically developed for the life sciences industry and is considered an industry-leading solution. Blockchain technology enables every medication transaction to be immutably recorded and grants all authorised participants in the supply chain transparent access to verification data.

## Sources

- [NABP Acquires Patient Safety Tool From Chronicled Inc.](https://nabp.pharmacy/news/news-releases/nabp-acquires-patient-safety-tool-from-chronicled-inc/)
- [NABP Acquires Patient Safety Tool From Chronicled Inc.](https://www.globenewswire.com/news-release/2023/06/14/2688321/0/en/NABP-Acquires-Patient-Safety-Tool-From-Chronicled-Inc.html)
- [FDA DSCSA Pilot Project Report](https://www.fda.gov/media/168283/download)